SAPPINIA SPP.: AN UPDATE

Sappinia spp.: An update

Sappinia is a free-living amoeba isolated from soil, dead plant material, freshwater, ponds, water supplies, surface water and the faecal material of various organisms such as cows, bats, reptiles, King penguin, and even humans.Of note, Sappinia was reported to be the causative agent in a case of non-granulomatous amoebic encephalitis, in an immuno

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Prenatal exposure to valproic acid induces alterations in the expression and activity of purinergic receptors in the embryonic rat brain

Purinergic signalling is involved in the control of several processes related to brain development, such as neurogenesis and gliogenesis, migration and differentiation ventilationstejp of neuronal precursors, synaptogenesis and synaptic elimination to achieve a fully wired and efficient mature brain.Therefore, any deregulation of purine-dependent s

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Meningococcal surveillance in Southeast Asia and the Pacific

Meningococcal disease is an uncommon infection associated with high case fatality rates, especially in some low resource countries.The burden of meningococcal disease in the Asia Pacific region is relatively low although likely to be underreported.Carriage rates of the causative bacteria, Neisseria meningitidis are also lower than in many other cou

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